Quinolines and derivatives
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Filtered Search Results
Selleck Chemical LLC Q-VD-Oph
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Q-VD-Oph (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1 3 8 and 9 Q-VD-OPh can inhibits HIV infection
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000449988 8-AMINOQUINOLINE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000449977 6-AMINOQUINOLINE 25G
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Medchemexpress LLC RCGD423 200mg | 108237-91-8 | 331.23 g/mol | 200 MG
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RCGD423 is a small-molecule gp130 modulator used in research to prevent articular cartilage degeneration and promote repair. It modulates gp130 signaling and activates downstream JAK/STAT pathways, and has been applied in cellular and animal studies to evaluate cartilage protection and repair mechanisms.
- Modulates gp130 signaling and activates JAK/STAT pathways.
- Demonstrated disease-modifying activity in cartilage injury and degeneration models.
- High purity listed (99.92%), suitable for biochemical and cellular assays.
- Chemical formula C15H11BrN2S; molecular weight 331.23 g/mol.
- For research use only; not for human or clinical use.
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![Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000097078.png-250.jpg)
Apexbio Technology LLC prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] 25mg
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Prostate apoptosis response protein PAR-4 2-7 is a short peptide targeting transcriptional regulation pathways It is designed to modulate transcription factor activity thereby influencing apoptosis mechanisms particularly in prostate cells PAR-4 2-7 exerts its biological activity primarily through interaction with transcription factors via a leucine zipper zinc finger domain facilitating apoptosis in transformed or malignant cells while sparing normal cells Based on these properties PAR-4 2-7 holds research potential in studies investigating tumor suppression mechanisms and transcription-mediated apoptosis regulation in oncology and therapeutic research
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eMolecules 4-BROMOPYRIMIDIN-2-AMINE 2.5G
5000170202 4-BROMOPYRIMIDIN-2-AMINE 2.5G
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Apexbio Technology LLC Zonisamide 68291-97-4 200mg
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Zonisamide (CAS 68291-97-4) is a small molecule antiepileptic agent characterized by its broad-spectrum anticonvulsant mechanisms It inhibits neuronal hyperexcitability primarily through blockade of voltage-gated sodium channels and T-type calcium channels Zonisamide also facilitates large-conductance calcium-activated potassium (BKCa) channel activity and modulates GABAergic glutamatergic and monoaminergic neurotransmission Due to its multifaceted pharmacological actions zonisamide is utilized in research focused on seizure disorders ion channel function and the modulation of central nervous system excitability
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428186 ACRIDINE ORANGE 10-N 5MG
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Chemscene ChemScene | 5-Quinolinecarboxylic acid | 10G | CS-W004029 | 0.98 | 7250-53-5| MFCD00047608 | 173.17
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ChemScene | 5-Quinolinecarboxylic acid | 10G | CS-W004029 | 0.98 | 7250-53-5| MFCD00047608 | 173.17
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eMolecules 5-BROMO-1H-INDAZOLE-7-CARBO 5G
5000225216 5-BROMO-1H-INDAZOLE-7-CARBO 5G
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TARGETMOL CHEMICALS INC Tandutinib 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50 0.22 uM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR. Purity 99.74%
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Apexbio Technology LLC LDK378 1032900-25-6 200mg
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LDK378 (CAS 1032900-25-6) is a potent inhibitor of anaplastic lymphoma kinase (ALK) a receptor tyrosine kinase within the insulin receptor superfamily It exhibits an in vitro IC50 of 200 pM for ALK and displays moderate to high inhibitory activity against a limited set of other kinases including IGF-1R (IC50 8 nM) InsR (IC50 7 nM) and STK22D (IC50 23 nM) LDK378 suppresses proliferation of Ba/F3 cells transfected with NPM-ALK fusion and Karpas 299 human lymphoma cells harboring NPM-ALK with IC50 values of 22 8 nM and 26 nM respectively The compound is widely used in preclinical studies to investigate ALK-driven signaling and its potential as a therapeutic target in oncology
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eMolecules ChemScene / Ethyl 2-hydroxyquinoline-4-carboxylate / 250mg / 654744479 / CS-0208320 / 0.000 / 5466-27-3 / MFCD02041443 / 217.224 / C12H11NO3
ChemScene / Ethyl 2-hydroxyquinoline-4-carboxylate / 250mg / 654744479 / CS-0208320 / 0.000 / 5466-27-3 / MFCD02041443 / 217.224 / C12H11NO3
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000383875 VII-31 10MM 1ML
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Apexbio Technology LLC Penicillin V potassium salt 132-98-9 200mg
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Penicillin V potassium salt (132-98-9) is a small-molecule inhibitor targeting bacterial cell wall peptidoglycan synthesis It is designed to inhibit this biosynthetic pathway thereby suppressing the growth of Gram-positive bacteria Penicillin V potassium salt exerts its biological activity primarily through inhibition of bacterial cell wall synthesis In microbial susceptibility assays Penicillin V potassium salt demonstrates inhibitory effects with IC50 values ranging from approximately 0 01 to 0 5 g/mL for sensitive bacterial strains Based on these pharmacological properties Penicillin V potassium salt holds research potential in studies investigating Gram-positive bacterial resistance mechanisms cell-wall targeting antibiotic actions and experimental models of upper respiratory tract infections including otitis media sinusitis pharyngitis and tonsillitis
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